What is IMUREGEN?

Miscellaneous

Mar 11
DNA

THE VALUE OF DNA/RNA NUCLEOTIDE SUPPLEMENTATION

The science which promotes healthy aging is designed to preserve the human body in a healthy state for as long a period as possible. Thus it seeks to maintain one’s mind and body mentally alert and physically active so that one can enjoy contentment throughout all of life, relatively free of stress.

One of the challenges to healthy aging is the ability for the body to defend itself against disease and in increasingly unfriendly environment. The present approach for dealing with health problems is to treat the symptoms rather than the cause of the disease or discomfort by drugs and/or surgery. Although this is an effective means for resolving a serious infection or a life-threatening circumstance it is not a panacea for resolving all medical issues.

It has been the vision of the scientific community to find a way to strengthen the immune system, similar to vaccination, so that it will be ready to destroy pathogens; Imuregen was created with this vision in mind. Based on long term experimental research and clinical studies in Europe, it has been confirmed that Imuregen has positive effects on the total regeneration of the body and immune system. It is especially suitable for persons who are under extreme physical or mental stress. It fosters the regeneration of liver tissue and mucous membranes of the digestive and respiratory systems. It also provides protection from viral and bacterial infections.

Imuregen offers a new means of strengthening the immune system and promoting cell regeneration. By using highly efficient natural substances, such as essential nucleotides, amino acids, oligopeptides and trace elements, Imuregen is able to increase the body’s immunity and effect cell regeneration. Imuregen is introduced into the digestive tract in active form thus allowing the body to absorb only the substances it needs for optimizing performance, avoiding stress and disease, and to improve metabolism during a disease. Imuregen regulates the body’s stamina by modulating the cellular and hormonal function of the immune system.

Imuregen supplementation is thus one of the most rejuvenating, immune enhancing, and tissue supporting regimens ever to be discovered.

Numerous published scientific studies indicate very significant health benefits from DNA and RNA component supplementation. Almost every system of the body has documentation of improved health, vitality, or function from providing supplements of these fundamentally important cellular elements, from infancy to advanced age. The following is a brief summary from the vast literature supporting the many published benefits of nucleotide supplementation in the diet.

Tissue Regeneration

In order to sustain health, virtually every tissue in the body must regenerate itself regularly. Having adequate supplies of all  the  nucleic acid bases may be one of the most significant limiting factors on whether a tissue will be able to express its greatest capacity for regeneration and self- repair.

Any tissue, in order to regenerate, requires the ability to make DNA and RNA to support the process of making new cells.

Providing readily absorbed and assimilated nucleotides can be one of the most powerful ways to assist any tissue to repair and renew itself.

Wound Healing

Several studies in wound healing have assessed the effects of supplemental nucleic acids on wound healing. Compared to the control group, those receiving the supplements showed more rapid healing, greater tensile strength of the skin, and significantly reduced scarring.

 

Endocrine Gland Repair

Some of the tiniest organs in the body have the most profound effects on our health and well being. These are the endocrine glands that secrete minute amounts of hormones into the blood without which every function of the body can suffer.

• The pituitary gland
• The adrenal glands
• The thymus gland
• The thyroid gland
• The salivary glands

Intestinal Integrity, Maturation, and Bowel

Flora

The intestinal lining replaces all of its cells every seven days. Only a single layer thick, this lining is highly dependent on a sufficient supply of nucleic acids to completely regenerate itself every week. If nutritional support is inadequate, defective regeneration of the intestinal mucosal lining impairs the enzymatic stages of digestion, which can lead to a vicious cycle of deteriorating digestion and nutritional status.

Upon administration of supplemental nucleotides, the appearance of the intestinal lining greatly improved, with regeneration of the height of the absorptive intestinal villi. In addition, the enzyme content and function of the Intestinal lining also greatly improved, permitting the animals to recover and thrive robustly.

 Regen – Antimicrobial Peptides and Proteins (AMPP)

AMPP’s have enormous importance for human health, because they kill microorganisms (bacteria, viruses, fungi, protozoa) on the interfaces between the external and internal environment of the body (intestine, lung, skin, urinary tract) and protects the circulatory system from the penetration of microbes (Yu et al 2010). AMPP regulate immune response and slows dangerous inflammatory response which are dangerous to the body.

HDL Cholesterol Levels

An additional finding in individuals who received nucleotide supplementation was an improvement in their blood lipid profiles. In particular, the individuals receiving added nucleic acids were found to have higher HDL cholesterol levels, the cholesterol fraction that protects against cardiovascular disease the higher the level.

 

Growth and Development

Studies in young laboratory animals have assessed the effects of supplementing DNA and RNA elements. Compared to control animals, the supplemented animals grew, developed, and increased muscle mass at a greater rate. Other vital proteins were also built more readily in the treated animals. The intestinal lining in particular matured more robustly in the supplemented animals. Research thus far indicates that the

tremendous need for nucleic acids in growth and development is strongly beneficially supported through supplementing these vital nutritional elements.

Cellular Immunity

Cellular immunity refers in particular to immune cells that have the role of identifying cells in the body that have become abnormal, so that the abnormal cells can be removed. The main cellular changes sought through the cellular immune system are the development of cancer cells or various types of intracellular infection. The goal of the cellular immune system is to eliminate cancer cells or infected cells before they can

become established in the body to cause serious illness. The main effectors of cellular immunity are cells that arise in the thymus gland. These cells are often called T cells for their thymic derivation, of which there are several types with varying functions. A special type of T cell called a cytotoxic T cell has the role of finding and sticking to abnormal cells, then releasing substances that selectively digest and clear the renegade cells.

Memory Enhancement

Many studies in animals and humans have found a dramatic improvement in memory function with nucleic acid supplementation. Whether it is the ability to remember the right pathway to get through a maze for a prize of cheese, or to remember facts and figures, giving supplements of DNA and RNA elements has highly significantly increased performance.

Perhaps most dramatically, one researcher has focused on giving nucleic acids to persons with dementia. Even with advanced cases, if he went to high enough delivery levels to his patients, in almost every case memory improvement was very significant. The doctor reported that even in advanced cases of dementia dramatic memory recovery occurred if high enough levels of nucleic acids were given.

Longevity

It is perhaps functional nucleic acid deficiency that limits our potential for healthy longevity more than any other single factor. Of all the interventions that have ever been attempted to increase the life span of mammals, no method ever studied has been more powerful for mammalian life extension than nucleic acid supplementation. Compared to other techniques that have increased longevity of experimental animals up to 50%, administering nucleic acids has doubled and even tripled the usual maximum life span.

Added ATP Benefits

ATP stands for adenosine triphosphate, perhaps the most important of all the nucleic acid derivatives in the body. Its effects are so powerful and essential to cellular function, a description of its unique properties warrants special attention. ATP is the fundamental currency of every cell in the body. Virtually every activity in the body that requires energy uses ATP as the source of power. Whether the function is building complex molecules from building blocks, maintaining the electric potential of cell membranes, or allowing muscle fibers to contract for mobility, speed, and strength, it is ATP that provides the electrochemical fuel.

The oxygenating effects of nucleotide supplementation combined with a supply of ATP is likely to be additive and even synergistic at helping cells throughout the body achieve higher energy potentials and more ideal energy balances.

Cellular Energy

There are two fundamental ways ATP is generated in the body, one very efficient and one very wasteful. Efficient ATP production occurs through aerobic metabolism in the mitochondria, tiny organs or organelles within the cell that burn fuels like fat and glucose to generate ATP. Aerobic means that oxygen is used to completely burn a fuel for maximum ATP production. For example, the complete combustion of a single glucose molecule to carbon dioxide

and water yields a rich harvest of 36 molecules of ATP. As nucleotides boosts cellular oxygen delivery, already making ATP production more efficient, the ATP has an ideal environment for further boosting cellular energy conditions; thus all the desirable ATP effects are likely to be even more potent.

The oxygenating effects of nucleotide supplementation combined with a supply of ATP is likely to be additive and even synergistic at helping cells throughout the body achieve higher energy potentials and more ideal energy balances.

Neurological Effects

ATP is the primary fuel that drives learning, memory, and concentration functions.

 

 

 

Cardiac Strengthening

The cyclic contraction of cardiac muscle is highly ATP intensive and thrives on aerobic metabolism. The combined oxygenation and ATP delivery effects of DNA/RNA formulas provide the heart with an enhanced energy supply for efficient function.

 

Muscle Performance

Skeletal Muscle also requires abundant quantities of ATP for muscular contraction. Supplemental ATP has been described as an explosive performance enhancer. Especially, if given with two other nutrient supporters of muscle function, creatine monohydrate and creatine pyruvate, muscle endurance, performance, and recovery can be significantly boosted.

Lung Function

ATP administration has been shown to have numerous beneficial effects on lung function, particularly the delicate lining membranes of the airways and alveoli.

In some conditions, the blood pressure in the vessels in the lungs can rise too high, a condition known as pulmonary hypertension. ATP binds to the lining of the pulmonary vessels and stimulates a cascade of events that cause the blood vessels to relax and lower the pressure.

Cystic fibrosis is one of the most common inherited genetic diseases. Impaired water and electrolyte secretion from the bronchial lining results in thick secretions that block the bronchial tubes and result in recurring infections. ATP has been found to increase electrolyte and water secretion with improved clearance of secretions, offering hope of a new and useful intervention in this often aggressively progressive condition.

Antitumor Effects

In test tube studies, adding ATP has shown the ability to inhibit the growth of several types of human cancer cell lines. The types of cancer cells inhibited include pancreatic cancer, colon cancer, melanoma, androgen-independent prostate cancer (i.e., not responsive to male hormone manipulation, the most aggressive variant), breast cancer, myeloid and monocytic leukemia (bone marrow derived tumors of blood forming cells), and multidrug resistant colon cancer. In contrast, normal cells from these tissues showed less inhibition of growth or no inhibition at all, suggesting that increasing ATP outside cells may have a selective inhibitory effect on several cancer cell lines.

Improved Stress Management

Under conditions of metabolic stress, such as depriving a tissue of oxygen through reduced blood supply, a rapid and massive depletion of ATP within cells occurs. REgen has been described as a ~natural defense system~ to protect the tissues from the effects of severe oxygen deprivation. These protective effects include improved function of energy generating mitochondria, better electrolyte transport, increased ATP within cells, reduced oxygen consumption, and improved function of messenger molecules within the cells.

Stress is a condition in which there is a generalized reduction of blood flow and oxygenation to tissues below that required for their function. If stress is sustained, the prolonged tension from internal or external stressors may cause various physical manifestations – e.g., asthma, back pain, arrhythmias, fatigue, headaches, irritable bowel syndrome, ulcers, and suppress the immune system”.

It can raise blood pressure, increase the risk of heart attack and stroke, increase vulnerability to anxiety and depression, contribute to infertility, and hasten the aging process.

Sexual Function

In human tissue studies, the increase of ATP and adenosine has been found to induce the smooth muscle relaxation that is essential for erectile function. In diabetic men, erectile dysfunction is common through several mechanisms. The erectile tissue of diabetic men has been found to be especially sensitive to the smooth muscle relaxation effects of ATP, offering them a hopeful avenue of recovery of erectile function.

 


 

 

What is in Imuregen®

INSTITUTE OF MICROBIOLOGY OF THE ASCR
Translation from Czech into English language

Immunology and Gnotobiology Sector
Institute of Microbiology of the Academy of Sciences Czech Republic
Videňská 1083
142 20 Prague 4

In Prague on 31.1.2002

IMUREGEN® is a product with significant bioactive effects. It is non-toxic [National Institute of Public Health, Prague], without mutagenic activity and exhibits immunoregulatory properties [Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, Jan Evangelista Purkyně Military Medical Academy, Hradec Králové, Regional Hygienic Station, Ústí nad Labem].

It has been approved as a Czech product by the Ministry of Health of the Czech Republic (HEM-350-29.10.1998-36469) and is patented and trademarked.

Imuregen® is prepared by auto-enzymatic digestion of animal tissues using a precisely controlled technological process. It contains a mixture of free essential amino acids [1], low-molecular peptides [2] and cationic proteins [3], nucleotides [4], and organically bound iron [5] and zinc [6] in optimal ratios.

  1. Amino acids are the building blocks of Amino acids that must be supplied to the body in the form of food are referred to as essential.
  2. Proteins are composed of several polypeptide chains, which consist of peptides (short chains of amino acids).
  3. Cationic proteins are low molecular weight proteins characterised by antimicrobial and antibiotic They are part of the natural immunity of the body.
  4. Nucleotides are the building blocks of nucleic Deoxyribonucleic acid (DNA) is contained in the core (nucleus), and in the cytoplasm of animal and plant cells, carrying the encoded characteristics of the organism in the form of genes, and ribonucleic acid (RNA), important for transcription and the ultimate manifestation of these properties.
  5. Iron (Fe) is an important trace element necessary for proper growth, development and functional maturation of cells and
  6. Zinc (Zn) is an essential trace element, ensuring the functionality of the immune

Bioactive properties of Imuregen®

The ingredients contained in Imuregen® are important to the growth and division of cells, and tissue construction. It plays a supporting role in liver disease, healing of wounds and fractures and restoration of the function of the digestive system after intestinal infection.

Immunoregulatory properties of Imuregen®

Imuregen® supports the overall anti-infective immunity of the body. It increases the readiness of the immune system by giving the body components, which are necessary for the development of protective and anti-inflammatory factors and antibodies, and which also inhibit the accompanying symptoms of allergic diseases.


Thanks to these immunoregulatory properties, Imuregen® is recommended as a preventive product before the onset of seasonal infectious diseases as well as a supportive product in the treatment of conditions where the body’s immunity is reduced for whatever reason.

Therefore, its regular use is suitable for children who do not yet have fully developed immune function as well as for the elderly with reduced efficiency of the immune system, and also during any states reduced efficiency of the immune system in adults (polluted environment, chemical plants, hard labour, challenging sports training, recovery from surgery, injuries and burns, starvation, or infectious and other diseases).

Use of Imuregen®

The balanced bioactive and immunoregulatory properties of lmuregenâ make it an ideal supportive dietary supplement that may be used alone in the form of drops, and capsules and tablets, or as an ingredient in food products. It does not affect the taste of food or aroma of beverages.

Conclusion

Preventive application of IMUREGEN® did not exhibit generally toxic effects on the body. Immunological tests focusing on the core symptoms of innate immunity (distribution of NK cells), specific immunity T and B component (relative proportions of cell subpopulations CD4, CD8 and IgM and IgG) and the formation of humoral IgM and IgG showed no inhibitory effects.

The product does not exhibit properties that would lead to excessive exhaustive stimulation of observed immunological parameters and unproductive immunostimulation, resulting in the exhaustion of the immune capacity of the body.

Tests demonstrate that the product has desirable sparing immunostimulatory properties and optimally selected time and preventive dosage application will increase the readiness of both natural and specific cellular and humoral immunity

 

Signed: RNDr. Petr Šima, CSc.

For Further Reading and all the studies behind this product:

Book FHP Nucleotides Comprehensive Independent Report

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